Laureano Simón Buela,Mirella G. Zulueta,Teresa Tusié
申请号：
US16063081
公开号：
US20200283850A1
申请日:
2016.12.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided is a method of assessing Gestational Diabetes Mellitus (GDM) susceptibility in a female human subject, the method comprising determining the identity of at least one allele at each of at least two positions of single nucleotide polymorphism (SNP) selected from: TCF7L2—；rs7903146； IGF2BP2—；rs4402960； CDKN2A/B—；rs10811661； SLC16A11—；rs13342232； FTO—；rs8050136； SLC30A8—；rs13266634； CDC123/CAMK1D—；rs12779790； KCNQ1—；rs2237892； CUBN—；rs11254363； CUBN—；rs1801222； FIGN—；rs2119289； FIGN—；rs982393； MTHFR—；rs1801131； MTHFR—；rs1801133； MTR—；rs1805087； and SLC19A1—；rs1051266, and/or an SNP in linkage disequilibrium therewith at r2>；0.8. Also provided are genotyping tools and risk assessment systems for use in the method of assessing GDM susceptibility.
