Gerben Albert Van T Klooster,Piet Tom Bert Paul Wigerinck,Sandra De Meyer,Lieven Elvire Colette Baert,Herman Augustinus De Kock
申请号:
US11911465
公开号:
US08557854B2
申请日:
2006.04.14
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for improving the pharmacokinetics of drugs, which are metabolized by cytochrome P450 monooxygenase is disclosed. More specifically it relates to a method for improving the pharmacokinetics of retroviral protease inhibitors and in particular for improving the pharmacokinetics of human immunodeficiency virus (HIV) protease inhibitors. A pharmaceutical composition and its use in the manufacture of a medicament for the inhibition or treatment of an HIV infection or AIDS in a human being are also part of the invention.