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Human monoclonal antibodies against interleukin 8 (IL-8)
专利权人:
Cormorant Pharmaceuticals AB
发明人:
Petersen, Jorgen,Hudson, Debra,Baadsgaard, Ole D.,Parren, Paul,Teeling, Jessica
申请号:
AU2003299641
公开号:
AU2003299641C1
申请日:
2003.12.16
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Isolated human monoclonal antibodies which bind to IL-8 (e.g., human IL-8) are disclosed. The human antibodies can be produced in a hybridoma, transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, hybridomas, and transfectomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
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