PURPOSE: A complex herbal medication extract composed of a Hedera helix leaf and a barberry root is provied to utilize as a medicinal composition for prevention and treatmentof an infectious disease caused by an influenza virus by checking survival rate when injected together with an anti-virus agent. CONSTITUTION: A medicinal composition for prevention and treatment of an infectious disease caused by an influenza virus contains a complex herbal extract with a complex herb medication composed of a Hedera helix leaf and a barberry root as an active component. a complex medicinal extract is a compound in which a dried weight ratio (w/w) of the Hedera helix leaf extract and the barberry root in 1-10:1 are mixed in a mixing ratio. The Hedera helix extract is a crude extract, a polar solvent extract, or a non-polar solvent soluble extract. The barberry extract is water, a low quality alcolhol with carbon number ranged from 1-4 such as methanol, butanol, an extract which is useful in a selected solvent from a mixed solvent or a bubbled butanolo extract. The medicinal composition for prevention and treatment of an infectious disease caused by an influenza virus contains the combination of the complex herbal medication extract composed of the Hedera helix leaf and the barberry root and an anti virus agent. [Reference numerals] (AA) Survival rate (%)； (BB) Time (day) after infection； (CC) Ivy leaf； (DD) Ivy leaf + coptis본 발명은 아이비엽 및 황련으로 구성된 복합생약 추출물을 유효성분으로 함유하는 조성물에 관한 것으로, 상세하게는 아이비엽 및 황련으로 구성된 복합생약 추출물은 인플루엔자 바이러스에 대한 억제활성을 실험한 결과, 강력한 억제활성을 나타냈고, 특히 기존 항바이러스제와의 병용투여시 높은 바이러스 억제 활성을 나타냄을 확인함으로써, 상기 조성물을 인플루엔자 바이러스에 의한 감염증의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하다.
