Wolfgang KUNZE;Christine WEST;Karen-Anne NEUFELD;Paul FORSYTHE;John BIENENSTOCK
发明人:
John BIENENSTOCK,Paul FORSYTHE,Christine WEST,Wolfgang KUNZE,Karen-Anne NEUFELD
申请号:
US16365899
公开号:
US20190299005A1
申请日:
2019.03.27
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Vagus nerve stimulation effective in treating mood disorders include application of bursts of vagus nerve stimulation pulses having an average inter-burst duration and an average inter-pulse duration within selected intervals. The effectiveness of test agents in treating mood disorders can be determined by monitoring the firing pattern induced by the test agents on the vagus nerve. Test agents capable of inducing a firing pattern of vagus nerve pulses with average inter-burst duration and average inter-pulse duration within the selected intervals are identified as useful in treating a mood disorder.