Various exemplary matrix metalloproteinase (MMP) inhibiting adjuncts for surgical devices are provided. In general, an implantable adjunct can be configured to be applied to tissue by a surgical stapler in conjunction with staples. The adjunct can have at least one medicant releasably retained therein that is configured to reduce a length of the epithelialization process. In other words, the at least one medicant releasably retained in the adjunct can be configured to speed up an inflammation stage of wound healing and/or a proliferation stage of wound healing and, accordingly, reduce an amount of time before a remodeling stage of wound healing begins. The at least one medicant can be configured to be released along the staple line defined by the staples.
