THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA
发明人:
Charles V. Rice
申请号：
US16530756
公开号：
US20190358256A1
申请日:
2019.08.02
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure describes compositions comprising β-lactam antibiotics and branched polyethylenimines (BPEI), having efficacy against various Gram-positive bacteria, for example Gram-positive bacteria having resistance against β-lactam antibiotics, one non-limiting example of which is Methicillin-resistant Staphylococcus aureus (MRSA). The compositions result in the resensitization of such resistant bacterial strains to traditional antibiotic therapies such as β-lactam antibiotics.
