CROMIE KAREN,DOMBRECHT BRUNO,ETTENBERG SETH,KOLKMAN JOOST,LI JING,MEERSCHAERT KRIS,STOVER DAVID RAYMOND,ZHANG JINGXIN
申请号：
ZA201205864
公开号：
ZA201205864B
申请日:
2012.08.03
申请国别(地区):
ZA
年份:
2013
代理人:
摘要：
The present invention relates to amino acid sequences that are directed against TRAIL cell surface receptor 2 (herein also &ldquo；DR5&rdquo；), as well as to compounds or constructs thereof, and in particular proteins and polypeptides and nucleotides that encode them (referred to herein in their entirety as &ldquo；NB agents&rdquo；) and fragments thereof, and pharmaceutically effective variants thereof, and their use in the diagnosis and treatment of DR5 associated diseases and disorders.
