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A complex composed of a tryptophan-substituted polysaccharide or a tryptophan derivative from a heparin-binding protein, pharmaceutical composition and its uses
专利权人:
ADOCIA
发明人:
GÉRARD SOULA,MARTIN GAUDIER,OLIVIER SOULA,RÉMI SOULA
申请号:
BRPI0913684
公开号:
BRPI0913684A2
申请日:
2009.09.28
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention relates to a complex consisted of a polysaccharide and an HBP, said polysaccharide being consisted from glycoside bonds of (1,6) and/or (1,4) and/or (1,3) and/or (1,2) type and functionalized with at least one salifiable or salified tryptophan derivative. The invention also relates to a pharmaceutical composition comprising a complex according to the invention and to the use of a polysaccharide consisted of glycoside bonds of (1,6) and/or (1,4) and/or (1,3) and/or (1,2) type and functionalized with at least one salifiable or salified tryptophan derivative, for the preparation of a pharmaceutical formulation of stable HBPs.
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