The Brigham and Women's Hospital, Inc.;Tokitae LLC;Massachusetts Institute Of Technology
发明人:
申请号:
EP15806483.2
公开号:
EP3154553A4
申请日:
2015.06.11
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Described are gastric residence structures that include an active substance. The gastric residence structures may include one or more arms that include a loadable polymeric component, an elastic polymeric component, and a separate linker component. The linker may connect the one or more arms with the elastic polymeric component. The gastric residence structures may be configured to be folded and physically constrained during administration and may be configured to assume an open retention shape upon removal of a constraint. The change between the folded shape and the open retention shape may be mediated by the elastic polymeric component that undergoes elastic deformation when the residence structure is in the folded shape and recoils when the gastric residence structure assumes the open retention shape.