KIM, YOUNG KWAN,PARK, SANG YUN,JOO, HYUN WOO,CHOI, EUN SIL
申请号：
PL14818620
公开号：
PL3013796T3
申请日:
2014.06.26
申请国别(地区):
PL
年份:
2020
代理人:
摘要：
The present invention relates to biaryl derivatives of Formula 1, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof The biaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in the liver or in muscle due to anti-inflammatory action in macrophages, lipocytes, etc., and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, obesity, non-alcoholic fatty liver, steatohepatitis, osteoporosis or inflammation.wherein, A, B, D, E, G, R<；sub>；1<；/sub>；, R<；sub>；2<；/sub>；, R<；sub>；3<；/sub>；, R<；sub>；4<；/sub>；, R<；sub>；7<；/sub>；, m and n are as defined herein.
