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METHOD OF ASSESSING WOUND CONTAMINATION AND INFECTION
专利权人:
ENVUE IMAGING INC.
发明人:
Edward P. BUCHANAN,David KHECHOYAN
申请号:
US16487426
公开号:
US20200029887A1
申请日:
2018.02.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present application discloses a method, using monoclonal antibodies or alternative fluorophore biomarkers, in combination with near-infrared fluorescence (NIRF) imaging, for assessment of the bacterial contamination and infection of an acute or chronic wound for prescribing medical treatments. The method includes applying a detection reagent containing at least one type of monoclonal antibody bonded to a fluorophore, wherein the monoclonal antibody binds to a unique receptor site of a bacteria in the wound and the monoclonal antibody is detected by a NIRF imaging system. The fluorescence signal of the wound is used to determine the concentration of bacteria in colony forming units (CFUs) to assess whether the wound needs further treatment or is ready for closure.
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