The invention relates to a set comprising an endoscope (1) with i) an elongated housing (H) defining an elongated gripping portion(2) having an internal passage (100) and ii) an insertion portion (3) communicating with said internal passage (100) and having a distal end (4), a work tool unit (30) having a work tool controller (5) and an elongated flexible manipulation tube (12) with a treatment instrument (6) at the distal end (D) thereof, said housing (H) and said work tool controller(5)having complementary engagement structures (7,8) for releasably connecting said work tool controller (5) to said housing (H)with said manipulation tube(12) received by said internal passage (100) and said insertion portion (3), said internal passage (100) extending from a proximal end (110) of said elongated housing (H) and through said elongated gripping portion (2), said engagement structure (8) of said elongated housing (H) being at said proximal end (110) thereof, said engagement structures (7, 8) being configured for preventing rotation of at least a base (18) of said work tool controller (5) relative to said housing (H) releasably connected with said work tool controller (5), wherein free rotation of said manipulation tube (12) relative to said base (18) is prevented, said work tool controller (5) being configured for advancing said manipulation tube(12) received by said insertion portion (3) when said work tool controller (5) is connected with said housing (H) from a retracted position to an advanced position relative to said insertion portion(3), said manipulation tube (12) having an inner cable (11), said inner cable (11) being connected to said treatment instrument (6) and being movable relative to said manipulation tube (12).L'invention concerne un ensemble comprenant un endoscope (1) ayant i) un boîtier allongé (H) définissant une partie de préhension allongée (2) présentant un passage interne (100) et ii) une partie d'insertion (3) communiquant avec ledit passage intern
