This disclosure relates to which the compound as Syk inhibitor is treating the purposes in various morbid states, including cancer and inflammatory conditions with them. In a particular embodiment, the structure of the compound is provided by Formulas I: wherein R1, R2, R3 and R4 are as described in the present application. The method that the disclosure also provides the pharmaceutical composition comprising compound of formula I or its pharmaceutically acceptable salt or eutectic and passes through the Syk illnesss mediated using these compounds and composition treatment.本公開涉及作爲Syk抑制劑的化合物和它們在治療各種疾病狀態中的用途，包括癌症和炎性病症。在具體實施方案中，所述化合物的結構通過式I給出：其中R1、R2、R3和R4如本申請所述。本公開還提供包含式I化合物或者其藥學上可接受的鹽或者共晶的藥物組合物和使用這些化合物和組合物治療通過Syk介導的病症的方法。
