A system and method of treating urinary incontinence including a catheter andinjection guide operatively disposed together. At least one needle is operativelydisposed within at least one lumen and at least one channel extending throughthe catheter and injection guide respectively. The injection guide is transformablefrom a pre-injection configuration for placement in the bladder to an injectionconfiguration for injection of a pharmaceutical such as botulinum toxin intothe bladder tissue. Upon introduction of the pharmaceutical to the bladder tissue,symptoms of incontinence are alleviated.