A guidewire for use in a medical procedure includes an elongate guide member (102) dimensioned for insertion within a body vessel of a subject. The guide member includes an elongate body segment (110) and a leading tip segment (106). The elongate body segment defines a longitudinal opening (120), and the leading tip segment is adapted and dimensioned to articulate relative to the elongate body segment about a single axis. A control element (118) extends through the longitudinal opening of the elongate body segment and is longitudinally movable through manual manipulation of a clinician to cause corresponding articulating movement of the leading tip segment.