A system and methods for functional brain mapping is provided. The method includes providing a set of time-series functional magnetic resonance imaging (fMRI) data acquired from a brain of a subject while performing a functional task and decomposing the set of time-series fMRI data into a set of task signals and a set of non-task signals using a model related to the functional task performed by the subject. The method also includes generating a task activity map using the set of task signals and generating a non-task activity map using the set of non-task signals. The method further includes producing a combination map by selectively weighting the task activity map and non-task activity map, and combining the selectively weighted maps, using a statistical parameter, in dependence of a threshold.
