Liposom zawierający cząsteczkę shRNA skierowaną na syntazę tymidylanową oraz jego zastosowanie

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专利权人:

Delta-Fly Pharma; Inc.

发明人:

ISHIDA TATSUHIRO,HUANG CHENG-LONG,WADA HIROMI

申请号：

PL12790050

公开号：

PL2716304T3

申请日:

2012.05.22

申请国别(地区):

PL

年份:

2018

代理人:

摘要：

This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3' end.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/