Novel Spacer Moiety for Poly(ehtylene Glycol) Modified Peptide Based Compounds

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专利权人:

Christopher P. Holmes

发明人:

Christopher P. Holmes,David Tumelty,Qun Yin

申请号：

US13079615

公开号：

US20120115796A1

申请日:

2011.04.04

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to a compound comprising a peptide moiety, a spacer moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The spacer moiety is between the peptide moiety and the water-soluble polymer moiety. The spacer moiety has the structure:—NH—(CH2)α—[O—(CH2)β]γ—Oδ—(CH2)ε—Y—wherein α, β, γ, δ, and ε are each integers whose values are independently selected.

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