Kyle W.H. Chan,Aparajita Hoskote Chourasia,Paul E. Erdman,Leah Fung,Frank Mercurio,Robert Sullivan
申请号:
US16438244
公开号:
US20200000814A1
申请日:
2019.06.11
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides compounds that modulate protein function, to restore protein homeostasis, and cell-cell adhesion. The disclosure provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of diseases, disorders, or conditions associated with a protein, are provided.