oral composition, and methods for preparing the oral composition, for targeting an active ingredient, for depositing a bacteriostatic or bactericidal material on oral surfaces, for retarding or preventing dental caries, method for occluding dental tubules, for treating a carious lesion, for calcify an exposed tooth pulp, and to calcify the base of or all of a hole or fissure in a tooth.
The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present invention also relates to methods for preventing or treating periodontal disease and caries which include delivering a therapeutically effective amount of an oral composition containing a polyguanidine compound into an oral cavity.
