ALEN, Jo,BOLAND, Sandro,BOURIN, Arnaud Pierre Jean,DEFERT, Olivier,LEYSEN, Dirk
申请号：
ES12759666
公开号：
ES2560830T3
申请日:
2012.08.31
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
A compound of the formula I or a stereoisomer, tautomer, racemic, salt, hydrate or solvate thereof； ** Formula ** Wherein, X is hydrogen or halogen； Y is -NH-C (>； = O) - or -C (>； = O) -NH-； each of Z1, Z2 and Z3 is independently selected from the group consisting of C, N, O and S； R1 is selected from the group comprising hydrogen, alkyl of 1 to 20 carbon atoms and cycloalkyl of 3 to 15 carbon atoms； R2 is selected from the group comprising hydrogen, alkyl of 1 to 20 carbon atoms, halogen and alkoxy of 1 to 20 carbon atoms； R3 is selected from the group consisting of alkyl of 1 to 20 carbon atoms, alkenyl of 3 to 20 carbon atoms, alkynyl of 3 to 20 carbon atoms, cycloalkyl of 3 to 15 carbon atoms, aryl, heteroaryl and heterocyclyl of 3 to 19 carbon atoms； wherein said alkyl of 1 to 20 carbon atoms, alkenyl of 3 to 20 carbon atoms, alkynyl of 3 to 20 carbon atoms, cycloalkyl of 3 to 15 carbon atoms, aryl, heteroaryl and heterocyclyl of 3 to 19 atoms of Carbon are optionally substituted with one or more substituents, selected from the group consisting of halo, hydroxyl, oxo, carbonyl, amino, amido, cyano, aryl, heteroaryl, cycloalkyl of 3 to 15 carbon atoms, heterocyclyl of 3 to 19 atoms of carbon, alkylamino of 1 to 20 carbon atoms, di (alkyl of 1 to 20 carbon atoms) amino, alkoxy of 1 to 20 carbon atoms, halo alkoxy of 1 to 20 carbon atoms, halo-alkyl of 1 to 20 carbon atoms, alkylthio of 1 to 20 carbon atoms, carboxylic acid, acylamino, alkyl esters of 1 to 20 carbon atoms, carbamate, thioamido, urea and sulfonamido； and n is 0 or 1.Un compuesto de la fórmula I o un estereoisómero, tautómero, racémico, sal, hidrato o solvato del mismo；**Fórmula** En donde, X es hidrógeno o halógeno； Y es -NH-C(>；=O)- o -C(>；=O)-NH-； cada uno de Z1, Z2 y Z3 está seleccionado independientemente del grupo formado por C, N, O y S； R1 está seleccionado del grupo que comprende hidrógeno, alquilo de 1 a 20 átomos de carbono y cicloalquilo de 3 a 15 átomos de carbono； R2 está sele
