CID-NUNEZ JOSE MARIA,OEHLRLCH DANIEL,TRABANCO-SUAREZ ANDRES AVELINO,TRESADERN GARY JOHN,VEGA RAMIRO JUAN ANTONIO,MACDONALD GREGOR JAMES,CID-NUNEZ Jose Maria,OEHLRlCH Daniel,TRABANCO-SUAREZ Andres Avelino,TRESADERN Gary John
申请号：
SI201030449
公开号：
SI2430022T1
申请日:
2010.05.11
申请国别(地区):
SI
年份:
2014
代理人:
摘要：
The present invention relates to novel triazolo[4,3-a]pyridine derivatives of Formula (I) wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 (&ldquo；mGluR2&rdquo；), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.
