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LENTIVIRAL VECTORS PSEUDOTYPED WITH MUTANT BAEV ENV GLYCOPROTEINS
专利权人:
发明人:
申请号:
EP12766315.1
公开号:
EP2761010B1
申请日:
2012.09.28
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention concerns a pseudotyped viral vector particle for transferring biological material into cells, wherein said vector particle comprises at least:&mdasha chimeric envelope glycoprotein which comprises or consists in a fusion of the transmembrane and extracellular domain of a baboon endogenous retrovirus (BaEV) envelope glycoprotein and the cytoplasmic tail domain of a murine leukemia virus (MLV) envelope glycoprotein or&mdasha modified BaEV envelope glycoprotein wherein the cytoplasmic tail domain is devoid of the fusion inhibitory R peptide.
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