Sihuan Pharmaceutical Holdings Group Ltd.;Xuanzhu Pharma Co., Ltd.
发明人:
Frank Wu,Bo Chen
申请号：
US15704542
公开号：
US20180000819A1
申请日:
2017.09.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to a CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers； a pharmaceutical formulation, pharmaceutical composition and kit comprising said CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers, and use of said CDK4/6 kinase inhibitor, or a pharmaceutically acceptable salt, ester, or solvate thereof, or their isomers. For example, the compounds of the invention are useful for reducing or inhibiting the activity of CDK4/6 kinase in a cell, and/or treating and/or preventing a cancer-related disease mediated by CDK4/6 kinase.
