Provided is a medicine dispensing and packing apparatus including a sheet feeding apparatus, a medicine putting unit, a sealing apparatus, and a control unit. The control unit controls the sheet feeding apparatus and the sealing apparatus to pack medicine. A plurality of packets formed by the sheet feeding apparatus and the sealing apparatus include a plurality of medicine-containing packets and a plurality of empty packets in which the medicine is not packed. The control unit controls the sheet feeding apparatus and the sealing apparatus to: form the plurality of empty packets upstream of the plurality of medicine-containing packets in the feeding direction; and form at least one empty packet of the plurality of empty packets such that the lengthwise size thereof is smaller than that of each of the plurality of medicine-containing packets.