#$%^&*AU2014268202A120141211.pdf#####ABSTRACT The invention is a proteinaceous construct comprising a Factor VIII molecule which is conjugated to a water-soluble polymer via carbohydrate moieties of Factor VIII, and methods of preparing same. In one embodiment of the invention, the water-soluble polymer is selected from the group consisting of polyethylene glycol (PEG), polysialic acid (PSA) or dextran. - 1-