您的位置: 首页 > 农业专利 > 详情页

Phenylisonicotinic acid derivative and pharmaceutical use thereof
专利权人:
キッセイ薬品工業株式会社
发明人:
滝川 靖,清水 和夫,飯塚 雅人,藤倉 秀紀,平栃 正博
申请号:
JP2010533908
公开号:
JP5563985B2
申请日:
2009.10.14
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
Disclosed is a compound useful as a prophylactic or therapeutic agent for diseases associated with abnormal plasma uric acid levels and the like.  Specifically disclosed are: a phenylisonicotinic acid derivative represented by formula (I), a prodrug thereof, or a salt thereof, which has a xanthine oxidase inhibiting activity and an URAT1 inhibiting activity and is useful as a prophylactic or therapeutic agent for diseases associated with abnormal plasma uric acid levels; and others.  In formula (I), R1 represents a cyano, a trifluoromethyl, or the like; R2 represents H, a fluorine, or the like; and R3 represents W, or a group represented by formula -X-Y-Z (wherein W represents H, a halogen, a hydroxy group, a cycloalkyl, a heterocycloalkyl, or the like; X represents a single bond, -NH-, -O-, or the like; Y represents an alkylene, or the like; Z represents H, a haloalkyl, a hydroxy group, an alkoxy, a cycloalkyl, a heterocycloalkyl, an aryl, or the like).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充