Edward Haeggström,Jouko Yliruusi,Kai Falck,Heikki Räikkönen,Jenni Pessi,Ilkka Lassila,Antti Meriläinen
申请号:
US15512070
公开号:
US10098842B2
申请日:
2015.10.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to a method and a device for producing nanoparticles of organic substances, in particular by controlled expansion of pressurized solutions. The method comprises: admixing the organic substance and a supercritical fluid to form a mixture at a first pressure; decreasing the first pressure gradually to a second pressure so that a flow of the mixture is formed and nucleation of the organic substance in the mixture is initiated; and, decreasing the second pressure to a third pressure, so that solidification of the fluid of the mixture, comprising the nucleated organic substance, is initiated. The device comprises: a pressure chamber (1) for a mixture of the organic substance and a supercritical fluid; a collection chamber (5) for the nanoparticles; an outlet tube (2) connecting the pressure chamber to the collection chamber (5); and, one or more second nozzles (6). The outlet tube is provided with a pressure controlling means (3) configured to control pressure of the mixture within the outlet tube and a first nozzle (4) configured to allow expansion of the mixture to the collection chamber.