Baptiste Leroy,Ruddy Wattiez,Christiane A. J. Huygen,Virginie Roupie,Marc Govaert,Isabelle Georis
申请号:
US12513802
公开号:
US08470339B2
申请日:
2007.11.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention discloses new antigens of Mycobacterium avium subsp. paratuberculosis, antigenic compositions comprising at least two of said antigens, as well as epitopes, antibodies or hypervariable fragments thereof and nucleotide sequences coding for them. The present invention also concerns their use in diagnosis and/or vaccination against Mycobacterium avium subsp. paratuberculosis, in mammals, and in particular in cattle, but also in sheep and caprines. The invention also concerns their potential application in diagnosis and/or vaccination against Crohns disease in human.