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immunotherapeutic method for prostate cancer treatment
专利权人:
PANTARHEI BIOSCIENCE B.V.
发明人:
HERMAN JAN TIJMEN COELINGH BENNINK
申请号:
BR112013004389
公开号:
BR112013004389A2
申请日:
2011.08.29
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The invention relates to treatment of prostate cancer and metastases thereof. More specifically, the invention relates to immunogenic polypeptides comprising at least a portion of a prostatic tumor cell-associated protein or immunologically active variants thereof and to nucleic acids encoding such polypeptides and to the use thereof in immunotherapeutic methods of treatment of prostate cancer. Said immunogenic polypeptides are provided by the zona pellucida (ZP) (glyco)proteins. ZP (glyco)proteins and fragments thereof that can induce a CD8+ and/or CD4+ T cell response as well as nucleic acid sequences encoding them can suitably be used in the present immunotherapeutic strategies.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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