A method for optimized selection of a bicycle saddle from a population of different bicycle saddles includes the steps of providing a database composed of a set of physical elements corresponding to the population of different saddles, subdividing the set into a plurality of subsets according to predetermined geometrical and/or functional characteristics, collecting a plurality of anatomical parameters of a user to obtain corresponding data, and selecting one of the subsets having corresponding optimized characteristics according to the data. The geometrical and/or functional characteristics are selected from the group that includes the maximum plan width, the presence and dimension of holes and/or superficial hollows, and the plan shape of the saddles. The parameters are collected on the user in an upright position and with the legs stretched. A system for anthropometric determination of one or more optimized bicycle saddles.