DELUCA, HECTOR F.,WILLIAMS, KATIE BETH,BARCYKA, KATARZYNA
申请号：
CA2622021
公开号：
CA2622021C
申请日:
2006.09.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention provides improved methods and compositions fortherapeutically controlling and/or reducing serum phosphate levels in animalsand mammalian patients. The methods comprise administering to the patient anamount of a dendrimer composition effective to prevent absorption ofsubstantial amounts of phosphate from the patient's GI tract. In a preferredversion, a dose of between 2.5 and 15 grams per day is effective to preventover 80% of phosphate present in the patient's GI tract from being absorbed.The dendrimer composition may comprise a hydrochloride, hydrobromide,hydroacetate or hydroanionic form.
