Method for delivering agents into cells using bacterial toxins

• 收藏
• 分享

专利权人:

President and Fellows of Harvard College

发明人:

R. John Collier,Bradley L. Pentelute

申请号：

US14732057

公开号：

US09850475B2

申请日:

2015.06.05

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention provides compositions and methods for delivering a bioactive moiety comprising at least one non-natural component into a cell cytosol of a eukaryotic cell. The bioactive moiety is linked to an A component of a bacterial toxin, a functional wild-type or modified fragment thereof, or an A component surrogate or mimetic. For delivery, the cell is contacted with the linked bioactive moiety and a corresponding B component of the bacterial toxin or a functional fragment thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/