A method and a device for secured retrieval of tissue from inside a patient body and a kit comprising the device. the device comprises a tube housing a movable cutter. The cutter controllably extends from the tube while allowing continued fluid communication. The device comprises a retractable enclosure with a supporting frame linked to an impermeable membrane comprising an opening. Amplitude of the supporting frame is controlled. The opening in the impermeable membrane is unseal when enclosure is expanded and, when the tissue is positioned within the enclosure, the opening is sealably closed in the impermeable membrane. The moveable cutter morcellates the tissue into tissue specimens when the opening in the impermeable membrane is sealably closed while amplitude of the supporting frame is reduced to compress the tissue specimens and the tissue specimens are able to transit in the fluid communication channel through a discharging aperture after morcellation.