Qiu-Ping Qin,Harri Takalo,Allan Milton Byrnard,Kirsten Marie Jakobsen
申请号:
US12503602
公开号:
US08535898B2
申请日:
2009.07.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X—Z-A′ wherein one of either A or A′ comprises a luminescent chelate and the other one of A or A′ comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.