ANTICORPS ANTI-PD-L1 ET LEURS UTILISATIONS

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专利权人:

I-MAB

发明人:

FANG, LEI,WANG, ZHENGYI,GUO, BINGSHI,ZANG, JINGWU

申请号：

CA3027209

公开号：

CA3027209A1

申请日:

2017.06.13

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Provided are anti-PD-L1 antibodies or fragments thereof. The antibodies orfragments thereof specifically bind to theimmunoglobulin C domain of the PD-L1 protein. In various example, theantibodies or fragments thereof include a VH CDR1 of SEQID NO: 1, a VH CDR2 of SEQ ID NO: 2, a VH CDR3 of SEQ ID NO: 3, a VL CDR1 ofSEQ ID NO: 4, a VL CDR2 of SEQ ID NO: 5,and a VL CDR3 of SEQ ID NO: 6, or variants of each thereof. Methods of usingthe antibodies or fragments thereof for treating anddiagnosing diseases such as cancer and infectious diseases are also provided.

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http://www.ckcest.cn/home/