Skakle, Janet M. S.,Buckland, Thomas,Hadden, Daniel J.,Gibson, Iain R.
申请号:
AU2008237711
公开号:
AU2008237711B2
申请日:
2008.04.11
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention provides a process for the preparation of a silicate andcarbonate co-substituted calcium phosphate material. The process comprisesthe steps of: forming a silicon and optionally carbon-containing calcium phosphateprecipitate by an aqueous precipitation method involving preparing an aqueoussolution comprising phosphate ions, silicate ions, calcium ions and optionallycarbonate ions, wherein the ratio of Ca/P and of Ca/(P+Si) in the solution is maintainedabove approximately 1.67 and heating the precipitate in an atmosphere comprisingcarbon and oxygen to form a silicate and carbonate co-substituted calcium phosphatematerial. The present invention also provides a synthetic carbonate and silicateco-substituted hydroxyapatite material, as well as a biomedical material.