CHESWORTH, Richard,MORADEI, Oscar Miguel,SHAPIRO, Gideon,JIN, Lei,BABINE, Robert E.
申请号:
EP20150842456
公开号:
EP3193608(A4)
申请日:
2015.09.17
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
Provided herein are compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein R1, R2a, R2b, R3 and Ring B are as defined herein, and Ring A is a group of Formula (A-i), (A-ii), or (A-iii): wherein R, R, R, R, and R are as defined herein. Compounds of the present invention are useful for inhibiting CARMl activity. Methods of using the compounds for treating CARMl -mediated disorders are also described.