Targeting hepatitis B virus (HBV) host factors

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专利权人:

发明人:

Abraham L. Brass,Miles C. Smith

申请号：

US15268119

公开号：

US09771590B2

申请日:

2016.09.16

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Described herein are methods of identifying host factors that modulate Hepatitis B virus (HBV) replication in mammalian, e.g., human cells, as well as factors identified by those methods, and methods of treating HBV infections by targeting those factors. Zinc finger, CCHC domain containing 14 (ZCCHC14) is an exemplary host factor.

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