COMPOSITION OF RECOMBINANT OR TRANSGENIC FACTOR VII, EACH MOLECULE OF FACTOR VII EXHIBITING TWO N-GLYCOSYLATION SITES WITH DEFINED GLYCAN MOIETIES农业专利-农业学术服务平台

发明人:: CHTOUROU, ABDESSATAR SAMI,阿布德萨塔克鲁图沙米,阿布德薩塔克魯圖沙米,NONY, EMMANUEL,艾玛努尔诺尼,艾瑪努爾諾尼,BIHOREAU, NICOLAS,尼可拉比贺罗,尼可拉比賀羅

摘要：: The invention is related to a composition of recombinant or transgenic Factor VII, each molecule of Factor VII of the composition exhibiting two N-glycosylation sites, wherein, among all the molecules of FVII of the composition, the rate of Galα1,3Gal glycan moieties is comprised between 0 and 4%. The invention is also related to a process for preparing such a composition of FVII.本發明是關於重組或基因轉殖因子VII之組成物,組成物之每一因子VII分子展現兩個N-糖化作用位置,其中組成物之FVII全部分子間Gal α 1,3Gal聚醣部分的比例介於0及4%之間。本發明也關於該FVII組成物之製備方法。