Kyle W.H. Chan,Paul E. Erdman,Leah Fung,Frank Mercurio,Robert Sullivan
申请号：
US15916752
公开号：
US20180264000A1
申请日:
2018.03.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides modulators of protein function, to restore protein homeostasis, including GSPT1 activity. The invention provides methods of modulating protein-mediated diseases, such as GSPT1-mediated diseases, disorders, conditions, or responses. Compositions are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as GSPT1-mediated diseases, disorders, and conditions, including cancer and astrogliosis.
