It regards the medicine composition in order this invention includes the cerium salt on the collagen matrix, and the carrier which is allowed dermatology to deal with the lesion of the skin. In addition, this invention offers also the process which manufactures that kind of dressing material the dressing material in order to deal with the lesion of the skin (dressing) by making freeze makes dry the intermediate composition, and the aforementioned intermediate composition in order to manufacture. In addition, in the dressing material in order this invention includes the cerium salt on the collagen matrix, to deal with the lesion of the skin, and the medicine composition of this invention or manufacturing of the dressing material, it regards also the use of the cerium salt which is combined with the collagen. Other feature of this invention in lesion of the aforementioned skin, is the method of dealing with the lesion of the skin by applying that kind of medicine composition or the dressing material. As for the composition or the dressing material of this invention, the toxin which it is related to the single cell protein in the human body or animal body or generally known HSP (the heat shock protein) the skin lesion where discharge participates The burn skin toxin (burned skin toxin) or LPC (the lipo protein mixture) the burn where formation participates The chronic ulcer skin lesion where the proteolytic enzyme is produced to excess The skin lesion where the dispersion which needs the control of overproduction of bleeding is difficult And gravely infection or fixation (colonize) it can be used by the local application in, the lesion of various types such as the skin lesion which is done.本発明は、コラーゲンマトリックス上のセリウム塩及び皮膚科的に許容される担体を含む、皮膚の病変を処置するための医薬組成物に関する。加えて、本発明は、皮膚の病変を処置するためのドレッシング材(dressing)を調製するための中間組成物、及び前記中間組成物を凍結乾燥させることにより、そのようなドレッシング材を調製するプロセスをも提供する。また、本発明は、コラーゲンマトリックス上のセリウム塩を含む、皮膚の病変を処置するためのドレッシング材、及び本発明の医薬組成物又はドレッシング材の調製における、コラーゲンと組み合わせたセリウム塩の使用にも関する。本発明の他の態様は、前
