Peter Aadal Nielsen,Gunnar Andersson,Olga Andersson
申请号：
US13387083
公开号：
US20120122144A1
申请日:
2010.08.10
申请国别(地区):
US
年份:
2012
代理人:
摘要：
There is provided insect screening models to determine gastrointestinal absorption of different chemical compounds in vertebrates, and in particular humans, in order to improve the compound screening procedures/processes in the early drug discovery process. This offers many advantages relative to prior technologies since insect models are more reliable tools for the decision-making process than the existing in vitro models, and will speed up the drug screening process and reduce the late phase attrition rate. Moreover, it will reduce the number of mammals sacrificed during the drug discovery phase.
