near Dublin;The Provost; Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth
发明人:
Gilmer, John Francis,Lally, Maeve,Clune-Moriarty, Louise
申请号:
AU2008339961
公开号:
AU2008339961B2
申请日:
2008.12.19
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Aspirin is one of the most widely used drugs in the treatment of inflammation, pain and fever. It has more recently found application in the prevention of heart attacks and stroke and is being studied as a cancer chemopreventative agent. Despite its value aspirin continues to be underutilized because it causes gastric bleeding. The technology under development potentially removes this problem. It is designed to reduce contact between the drug and the intestinal lining. An isosorbide aspirinate prodrug compound is thus provided. The compound has the general structure as shown in general formula (I) wherein Y is a C