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Quickly Disintegrating Foam Wafer with High Mass Per Unit Area
专利权人:
LTS Lohmann Therapie-Systeme AG
发明人:
Markus MÜLLER,Marius BAUER,Michael LINN
申请号:
US16619359
公开号:
US20200138714A1
申请日:
2018.06.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to flat dosage forms that disintegrate or dissolve in an aqueous environment and release at least one active ingredient in a body orifice or body cavity. The inventive dosages are formed from a polymer matrix in the form of a solidified foam having cavities and contain at least one pharmaceutical active ingredient. The inventive dosage forms further have a high mass per unit area in the region of 50 to 350 g/m2. Despite their high mass per unit area and the resulting high active ingredient loading during administration, these dosage forms exhibit a substantially improved mouthfeel in comparison to conventional film dosage forms. The invention also relates to methods for producing a dosage form of this type.
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