Compositions that include extracts from sources of immune modulators that include nanofraction immune modulator molecules (i.e., molecules having molecular weights of about 3,000 Da and less) are disclosed. These compositions may also include other immune modulators, such as transfer factor. Administration of compositions with extracts that include nanofractlon immune modulator molecules modulates the cell-mediated immunity (e.g., down-regulates undesired T cell activity) of a subject to whlch such compositions are administered. When admlnlstered wlth transfer factor, the combination of nanofraction immune modulator molecules and transfer factor down-regulates undesired T cell activity while increasing, or up-regulating, T cell activity against pathogens and other undesirable entities, such as cancer cells and other aberrant or mutated cells. Assays and assay techniques for evaluating the immune modulation capabllltles of varlous substances are also dlsclosed.本發明揭示一種包含免疫調節物之來源之萃取物的組成物，該等免疫調節物包含超微粒免疫調節物分子(亦即具有約3,000 Da及低於3,000 Da分子量之分子)。該等組成物亦可包含諸如轉移因子之其他免疫調節物。投予具有包含超微粒免疫調節物分子之萃取物之組成物，調節該等組成物所投予之個體之細胞媒介性免疫(例如下調(down-regulate)不想要的T細胞活性)。當與轉移因子一起投予時，超微粒免疫調節物分子與轉移因子之組合，在增加或上調T細胞對抗諸如癌細胞及其他異常或突變細胞之病原體及其他不想要的實體之活性的同時，亦下調不想要的T細胞活性。亦揭示用於評估各種物質之免疫調節能力之檢定及檢定技術。
