A drug eluting device and a manufacturing method thereof, the drug eluting device comprising a base (1) and a drug-carrying layer (3); the base (1) having an outer surface (102), a lateral surface (103) and an inner surface (101); the drug-carrying layer (3) comprising a drug carrier and an active drug (301); the outer surface (102), lateral surface (103) and inner surface (101) of the base (1) all being covered by the drug-carrying layer (3); the active drug (301) only being distributed on at least a portion of the areas of the drug-carrying layer (3) covering the outer surface (102) and lateral surface (103), and, in the depth direction of the at least portion of areas, the concentration of the active drug (301) at a side adjacent to the base (1) being greater than the concentration of the active drug (301) on a side furthest from the base (1), and an area of the drug-carrying layer (3) disposed at the inner surface (101) of the base (1) not containing the active drug (301). The drug eluting device has a relatively long active-drug release period, and has a relatively low risk of blood clots.La présente invention concerne un dispositif d'élution de médicament et son procédé de fabrication, le dispositif d'élution de médicament comprenant une base (1) et une couche de support de médicament (3) ; la base (1) comportant une surface externe (102), une surface latérale (103) et une surface interne (101) ; la couche de support de médicament (3) comprenant un support de médicament et un médicament actif (301) ; la surface externe (102), la surface latérale (103) et la surface interne (101) de la base (1) étant toutes recouvertes de la couche de support de médicament (3) ; le médicament actif (301) étant uniquement réparti sur au moins une portion des zones de la couche de support de médicament (3) recouvrant la surface externe (102) et la surface latérale (103), et, dans le sens de la profondeur desdites portions de zone, la concentration du médicament actif (301) au niv