The present invention provides novel antibodies that specifically bind to CD3 and uses thereof. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.本發明提供特異性結合至CD3之新穎抗體及其用途。本發明亦提供利用本文所提供之該等抗體及抗原結合片段之治療及診斷方法。