Virginia Tech Intellectual Properties, Inc.; Inc.;Iowa State University Research Foundation, Inc.;Virginia Tech Intellectual Properties
发明人:
Meng, Xiang-Jin,Fenaux, Martijn,Halbur, Patrick G.
申请号:
LT10184702
公开号:
LT2264050T
申请日:
2002.12.11
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
The present invention relates to an immunogenic polypeptide product which is obtainable by expressing infectious chimeric DNA clones of porcine circovirus (PCV). The present invention also relates to corresponding vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone is constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position.